Hypophosphatemia can occur when there is decreased phosphorus intake (decreased intestinal absorption or increased gastrointestinal losses), or excess renal wasting from renal tubular defects or hyperparathyroidism. In the case of cellular shifts, total body phosphorus may not be depleted. By convention, hypophosphatemia is often graded as mild (< 3.5 mg/dl), moderate (< 2.5 mg/dl) and severe (< 1.0 mg/dl). Moderate and severe hypophosphatemia will generally only occur when there are multiple problems. The causes of hypophosphatemia are shown in Box 2.
Clinical manifestations regarding hypophosphatemia
Hypophosphatemia is a very common searching for found in 3% of all of the hospitalized customers, 10% from hospitalized alcoholic clients, and you will 70% out-of ventilated ICU customers twenty five . Warning signs of hypophosphatemia are often only observed in people with modest otherwise significant hypophosphatemia and can include muscle mass exhaustion (and you can issue weaning off ventilator), hemolysis, impaired platelet and you will WBC mode, rhabdomyolysis, and in infrequent cases neurological conditions. Continue reading